2157 Main St.
Buffalo, NY 14214
24/7 Emergency Department
9:00 a.m. - 9:00 p.m.
Always Open
Monday – Friday: 8:00 a.m. to 4:00 p.m.
Monday – Friday: 7:30 a.m. to 3:30 p.m.
Monday – Friday: 7:30 a.m. to 3:30 p.m.
Monday – Friday: 8:00 a.m. to 5:00 p.m.
Saturday: 8:00 a.m. to 1:00 p.m.
Monday – Friday: 8:00 a.m. to 4:00 p.m.
Saturday: 9:00 a.m. to 10:00 a.m.
Monday – Friday: 7:00 a.m. to 3:30 p.m.
Saturday: 7:30 a.m. to 11:30 a.m.
Recognized as one of the best bariatric surgery programs in the nation by HealthGrades®, the Sisters of Charity Hospital Bariatric Program offers personalized care, education and support to ensure your surgery is a success.
Sisters of Charity Hospital is unlike any other maternity hospital in Western New York. Our personal approach and genuine love for what we do makes Sisters Hospital the ideal setting for families choosing where to deliver their babies.
Whether you need Pap smear or mammography screenings, family planning, are pregnant, have been diagnosed with ovarian cancer or have incontinence, the Sisters of Charity Hospital women's services care teams are here for you.
At Catholic Health, our network of hospitals continues to set the standard for vascular care in Western New York. Our vascular team includes highly skilled board certified vascular surgeons and endovascular specialists who provide care for vascular conditions.
Whether you’re coming in as a patient or visiting a loved one, we want you to have all the information you need to put your mind at ease. From where to park to how to order a meal, read up on our policies and suggestions for your stay!
Transparency is built into our culture, and we want you to have access to all the information you need regarding your visit to a Catholic Health hospital.
"I brought my husband to the ER at sisters with trepidation. Each person who attended to my husband was amazing! We were treated with professionalism and dignity. From the front desk to the ER rooms, to the floor. Very positive experience. The hospital and rooms were cleanly and the ER rooms as well."
Katherine B.
"The nursing staff, anesthesiologist, housekeeping and dietary staff were all kind and wonderful. I also am catholic so after my surgery I had a lady come in and pray with me which I appreciated. I've also been known for getting infections after surgery and when I tell you a lady came in with a black light making sure their were no germs in my room and it was clean, now that is what you call a good hospital. I would definitely prefer to go here for my operations over any other hospital. Thank you Sisters Hospital and all the staff for making my stay a good one!"
Shannon L.
"Came to the Emergency room with continued abdominal pain after surgery a week ago and got seen right away. My nurse was very nice and attentive. The doctors ordered every test needed to find what was wrong and they did. Definitely recommend Sisters Hospital over any other in the area."
Bryn H.
RN Hiring Event! Sisters of Charity Hospital
November 17, 2025 10:00 am - 2:00 pm
Sisters of Charity Hospital, 2157 Main St, Buffalo, NY 14214, USA
Sisters Hospital, Main Street Campus is known for its beloved maternity care program featuring a level III NICU and its advanced vascular surgical program. The hospital’s St. Joseph Campus is also nationally recognized for its leading orthopedic care. With two medical campuses serving Buffalo and its surrounding areas, Sisters of Charity Hospital provides a range of exceptional medical and surgical treatments.
To join this amazing nursing team, join us for open interviews at Sisters Hospital today!
Don't forget to ask about our sign on bonuses worth up to$25,000!
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